To handle something skillfully or successfully; to manage or do well.
緊張するけど、明日の面接でうまくやれるように準備しておく。
I'm nervous, but I'll prepare so I can do well in tomorrow's interview.
彼はどんな問題でも冷静に対処してうまくやるタイプだ。
He's the type who calmly deals with any problem and manages well.
チームで助け合えば、きっとうまくやれるはずだ。
If the team helps each other, we should definitely be able to do well.