A respectful, honorific way to refer to one's or someone else's grandmother.
おばあさま、お元気でいらっしゃいますか。
Grandmother, how are you? (polite)
式典で彼はおばあさまに深々とお辞儀をした。
At the ceremony he bowed deeply to his grandmother.
手紙には『おばあさまへ』と丁寧に書いた。
He wrote 'To Grandmother' politely in the letter.
A respectful term for an elderly woman; can be used for an old woman whether or not she is one's relative.
駅で道に迷っているおばあさまを駅員が助けていた。
A station attendant was helping an elderly woman who was lost at the station.
ご近所のおばあさまはいつも優しく声をかけてくださる。
The elderly woman next door always speaks kindly to us.