A polite way to refer to the person who lives opposite your house; commonly used in everyday conversation.
お向かいさんが引っ越してきたので、挨拶に行った。
The person across the street moved in, so I went to greet them.
お向かいさんは毎朝ゴミ出しを手伝ってくれる優しい方だ。
Our neighbor across the way is a kind person who helps take out the trash every morning.
向こうのお向かいさんに子どもが生まれたと聞いた。
I heard that the neighbor across from us had a baby.