To fray, splinter, or develop small splinters — used for wood, paper, or the skin of fingertips.
古い板の端がささくれていて危ない。
The edge of the old board is splintered and dangerous.
寒さで指の皮がささくれて痛い。
The cold has made the skin on my fingers crack and it's painful.
段ボールをよく扱うと端がささくれることがある。
Handling cardboard a lot can make its edges fray or splinter.
To become irritable or edgy; to be in a prickly mood and get annoyed easily.
疲れているときはすぐささくれて人に当たりやすい。
When I'm tired I get on edge easily and take it out on others.
最近彼はささくれていて、冗談にも冷たく反応する。
He's been touchy recently and reacts coldly even to jokes.