A connective phrase referring to the preceding statement, meaning 'even so' or 'despite that' (often used in spoken language; commonly appears in set phrases like 'それを承知で').
危険だと分かっていた。それを承知で彼は作業を続けた。
He knew it was dangerous. Even so, he continued the work.
締め切りが短い。それを踏まえて、優先順位を決めよう。
The deadline is short. With that in mind, let's decide the priorities.
彼は謝った。それを受けて、被害者側は許すかどうか議論した。
He apologized. In response to that, the victims discussed whether to forgive him.