In the end; after all is said and done — indicating the final outcome or conclusion after considering everything.
いろいろ検討したが、とどのつまり予算が足りないという結論になった。
We examined many options, but in the end the conclusion was that the budget was insufficient.
とどのつまり、彼は自分のミスを認めなかった。
After all, he didn't admit his mistake.
いろいろ迷ったが、とどのつまり行かないことにした。
I was indecisive, but in the end I decided not to go.