An adverb meaning 'in any case' or 'at any rate,' used to emphasize that something should be done or considered above all else (similar to とにかく).
とにもかくにも、まず安全を確保することが必要だ。
In any case, securing safety first is necessary.
問題の原因は後で調べるとして、とにもかくにも対処しよう。
We can investigate the cause later; for now, let's deal with it anyway.
彼は忙しくても、健康にはとにもかくにも気をつけている。
Even though he's busy, he takes care of his health above all.