An expression asking what the current situation is or what's happening. Often contracted in colloquial speech to 'どうなってる'.
会議が遅れているみたいだけど、今プロジェクトはどうなっている？
The meeting seems delayed—so what's the status of the project now?
携帯が壊れたみたい。写真はどうなっているか確認してくれる？
My phone seems broken. Can you check what's happened to the photos?
電車が止まっているらしい。今、運行はどうなっているか駅員に聞いてみよう。
It seems the train has stopped. Let's ask the station staff what's going on with operations now.
（子どもがぐったりしているとき）熱はある？様子はどうなっているの？
(When a child is listless) Do they have a fever? What's their condition like?