An expression meaning 'no matter how you look at it' or 'by all appearances,' used to indicate that something seems certain from any perspective.
どう見ても間違いだ。
It's obviously a mistake.
その写真はどう見ても合成にしか見えない。
No matter how you look at that photo, it only looks like a composite.
どう見ても彼女は疲れている。休ませたほうがいい。
She clearly looks tired. It's better to let her rest.