Polite honorific (masu-form) of なさる / "to do"; used to speak respectfully about someone else's actions (present/future sense).
来週のご予定はどのようになされますか。
How will your plans for next week be arranged?
部長はその問題をどうなされますか。
How will the department head handle that issue?
彼女はいつも仕事を丁寧になされます。
She always does her work carefully.