A siren — the loud warning device/sound used by ambulances, fire engines, or to signal alarms and emergencies.
救急車のサイレンが夜中に聞こえた。
I heard an ambulance siren in the middle of the night.
工場のサイレンは毎朝8時に鳴る。
The factory siren sounds at 8 a.m. every morning.
町中に空襲警報のサイレンが響いた(歴史的文脈で使う表現)。
Air-raid sirens echoed throughout the town (used in a historical context).