To feel irritated, offended, or angry (colloquial).
あの言い方には本当にむかついた。
That way of speaking really irritated me.
彼の態度を見てむかついて席を立った。
Seeing his attitude made me angry, so I got up.
はっきり言ってむかつくけど、ここは冷静に対処しよう。
Frankly, it's infuriating, but let's handle this calmly.
To feel sick or nauseous; to experience queasiness.
船酔いでむかついてきたから外の空気を吸いたい。
I'm feeling nauseous from seasickness, so I want to get some fresh air.
この料理の匂いがきつくてむかつく。
The smell of this dish is strong and makes me feel sick.