After a long time; used to indicate that something happens or that people meet again after a long interval (often used colloquially).
久々に友達と会って、話が尽きなかった。
I met my friend after a long time and we couldn't stop talking.
久々の休みで旅行に行く予定だ。
I plan to go on a trip during my first break in a long time.
ピアノを久々に弾いたら、指が思うように動かなかった。
When I played the piano after a long time, my fingers didn't move as I wanted.