A proverb-like expression meaning 'you only live once'; often used to encourage living boldly or without regrets.
人生一度きりだから、やりたいことに挑戦しようと思う。
Since you only live once, I think I'll try what I want to do.
彼は『人生一度きり』と言って仕事を辞め、海外に旅立った。
He said 'you only live once', quit his job, and set off abroad.
『人生一度きり』という言葉は、若者だけでなく年配の人にも響くことがある。
The phrase 'you only live once' can resonate not only with young people but also with older people.