In any case; anyhow; regardless of the circumstances—used to summarize or move to a conclusion.
何にせよ早めに決めたほうがいい。
In any case, it's better to decide early.
詳しい理由は後で話すとして、何にせよ行動を起こすべきだ。
Putting the details aside for now, in any case we should take action.
何にせよ返事は翌週中にお願いします。
In any case, please reply sometime next week.
何にせよ、まずは安全を確保しよう。
Anyway, let's make sure we're safe first.