To use different things appropriately for different purposes or situations; to distinguish usage according to context.
敬語と普通の言葉を相手や場面に応じて使い分けることは大切だ。
It's important to use honorific and plain language according to the person and situation.
このソフトには初心者向けと上級者向けの機能があり、用途によって使い分けられる。
This software has features for beginners and advanced users, and they can be used depending on the purpose.
文章では言葉遣いを状況に応じて使い分ける必要がある。
In writing, you need to adjust your choice of words according to the situation.