generally; overall; broadly speaking (applies to a wide range or most cases)
この病気は高齢者に全体に多く見られる。
This illness is generally seen more in the elderly.
全体にやる気はあるが、細部に注意が必要だ。
Overall there is motivation, but attention to details is needed.
全体にわたって規則が改定された。
The rules were revised throughout (across the board).