Advantages and disadvantages; the interests (gains or losses) of parties involved in a situation.
交渉では双方の利害を調整する必要がある。
In negotiations it is necessary to reconcile the interests of both parties.
利害が対立して合意に至らなかった。
Their interests conflicted, and they couldn't reach an agreement.
個人的な利害で判断してはいけない。
You must not make decisions based on personal interests.