A four-character idiom meaning a person who has no relatives anywhere; completely alone without family or support.
親を早くに亡くした彼は天涯孤独の身だ。
Having lost his parents early, he is without any relatives.
天涯孤独の老人が町で静かに暮らしている。
An elderly person with no relatives lives quietly in town.
彼女は天涯孤独という状況でも前向きに生きている。
Even in a situation of having no relatives, she lives positively.