Husband and wife; a married couple. A somewhat formal expression, not usually used for one's own family.
社長夫妻が式に出席した。
The company president and his wife attended the ceremony.
ご夫妻でご出席いただければ幸いです。
We would be pleased if you and your spouse could attend.
夫妻は地域のイベントを支援している。
The couple supports local events.