The disappearance of a person whose whereabouts become unknown; going missing or absconding (used often in news or police contexts).
数日前から彼が失踪していると家族が警察に通報した。
The family reported to the police that he has been missing for several days.
会社の金がなくなった後、社長が失踪したという噂がある。
There are rumors that the company president absconded after the company funds disappeared.
この事件は未解決の失踪事件として扱われている。
This case is being treated as an unresolved disappearance.