(colloquial) one's wife; a familiar/affectionate way to refer to a married woman (often used for one's own wife).
うちの嫁さんは料理がとても上手だ。
My wife is very good at cooking.
昨日、嫁さんと映画を見に行った。
Yesterday I went to see a movie with my wife.
彼の嫁さんはいつもにこにこしている。
His wife is always smiling.