A psychological feeling of being isolated or lacking social connection; often includes feelings of loneliness or alienation.
大学進学で地元を離れてから、強い孤独感を感じることが多くなった。
Since leaving for university, I've often felt a strong sense of loneliness.
長期の出張で家族と離れ、孤独感に悩む人もいる。
Some people suffer from loneliness when separated from their families on long business trips.
SNSを使っても孤独感が深まる場合がある。
Using social media can sometimes deepen one's sense of loneliness.
彼の孤独感は友人との会話で少し和らいだ。
His sense of loneliness eased a little through conversations with friends.