Fate or destiny; a predetermined course of events often regarded as unavoidable.
彼はそれが宿命だと受け止めている。
He accepts it as his fate.
家族の宿命を背負う覚悟が必要だ。
You need the resolve to bear the family's destiny.
宿命を変えることはできるのだろうか。
I wonder if fate can be changed.