To be distressed, worried, or pained emotionally; used when someone's heart aches over something.
子供が病気だと聞いて、母は心を痛めた。
Hearing that her child was ill, the mother was distressed.
あのニュースは多くの人の心を痛めた。
That news pained many people.
友達の失敗を見て心を痛める必要はないよ。
You don't need to be so upset about your friend's failure.