An idiomatic expression meaning one cannot get involved or cannot afford something — beyond one's reach (because of price, strength, danger, etc.).
そのブランドの時計は高くて手が出ない。
That brand's watch is too expensive; I can't afford it.
相手が強すぎて試合ではこちらは手が出ない。
The opponent was too strong, so we couldn't make a move in the match.
危険な地域なので個人で手が出ない問題だ。
It's a dangerous area, so it's not something an individual should get involved in.
限定品は人気で手が出ないことが多い。
Limited-edition items are often so popular that they're out of reach.