Loss and gain; advantage and disadvantage — considering whether an action or choice is beneficial or harmful.
彼はいつも損得で物事を考えるタイプだ。
He is the type of person who always considers things in terms of gain and loss.
短期的な損得だけで判断せず、長い目で考えよう。
Don't judge only by short-term gains and losses; think long-term.
損得勘定を抜きにして友情を大切にしたい。
I want to value friendship without thinking about gain or loss.