To rub; to chafe; to strike (a match); to file; to scour (glass).
背中を擦ると気持ちがいい。
Rubbing your back feels good.
マッチを擦って火をつけた。
He struck a match to light it.
ガラスにこびりついた汚れを布で擦った。
I rubbed the stubborn dirt on the glass with a cloth.
(colloquial) To squander one's money; to run through one's fortune (e.g., by gambling).
彼は給料を全部擦って、今月は金がない。
He squandered his entire paycheck and has no money this month.
ギャンブルで家族の貯金を擦った。
He ran through the family's savings gambling.