Change of course — altering direction of movement or shifting a policy/strategy; can be literal or figurative.
会社は市場の変化を受けて事業の方向転換を決めた。
The company decided to change its business direction in response to market changes.
交差点で方向転換する際は後方確認を忘れないでください。
When changing direction at an intersection, don't forget to check behind you.
政治家は選挙後に政策の方向転換を余儀なくされた。
The politician was forced to shift policy direction after the election.