Dirt, filth, stain, or spot—any kind of soiling on surfaces, clothing, objects, or even figuratively on a reputation.
そのシャツの襟に黒い汚れが付いている。
There's a black stain on the collar of that shirt.
窓の汚れは拭けばすぐ落ちる。
Window dirt comes off quickly if you wipe it.
彼のスキャンダルは会社の評判に汚れを残した。
His scandal left a stain on the company's reputation.
入浴後は皮膚の汚れをしっかり落とすことが大切だ。
After bathing, it's important to properly remove dirt from the skin.