Forcibly; doing something in a pushy or coercive way, often without regard for someone's wishes (colloquial, similar to 無理やり).
彼は無理くり飲ませられて具合が悪くなった。
He was forced to drink and felt sick afterwards.
無理くり予定を変更させられて困った。
I was forced to change my plans and it caused trouble.
そんなに無理くり笑わなくてもいいよ。
You don't have to force yourself to smile like that.