Distant or estranged from someone; having little closeness or familiarity in a relationship.
最近、兄とは疎くなってしまった。
Lately I've grown distant from my older brother.
彼女は家族との付き合いが疎い人だ。
She is someone who doesn't keep close ties with her family.
都会的な付き合いには疎いタイプだ。
He's the kind of person who is unfamiliar with city social life.
Unfamiliar with or ignorant about something; lacking knowledge or experience (commonly used as '〜に疎い', e.g. '疎い about politics').
私は歴史に疎いので、詳しい人に教えてもらった。
I'm not knowledgeable about history, so I asked someone well-informed to teach me.
彼は最新のIT事情に疎い。
He is out of touch with the latest IT developments.
地理に疎い友達に地図を見せた。
I showed the map to my friend who is bad at geography.