Deeply felt or keen; expressing an acute, heartfelt sentiment that strikes one strongly.
被災者の話を聞いて、痛切に支援の必要性を感じた。
Hearing the victims' stories made me keenly feel the need for assistance.
別れの言葉が痛切に胸に響いた。
The words of farewell struck me to the heart.
彼の失敗は痛切な教訓となった。
His failure became a poignant, hard-learned lesson.