To sever ties or cut off a relationship with someone, especially relatives, spouses, or close acquaintances.
彼は借金問題で家族と縁を切られてしまった。
He was cut off by his family because of debt problems.
長年の友人と些細なことで縁を切るのは辛い。
It's painful to cut ties with a long-time friend over something trivial.
彼女は暴力を振るう元夫と縁を切る決意をした。
She decided to cut ties with her abusive ex-husband.