Skin — the body’s outer covering (general term for the skin).
冬は肌が乾燥しやすいので、保湿が大切だ。
In winter the skin tends to dry out, so moisturizing is important.
その薬は肌に直接塗るタイプですか？
Is that medicine the type you apply directly to the skin?
敏感肌の人は化粧品を選ぶとき注意が必要だ。
People with sensitive skin need to be careful when choosing cosmetics.
The body in the context of intimate physical contact — used in expressions about physical closeness (e.g., '肌を許す').
恋人同士になると、自然と肌の触れ合いが増えることがある。
When people become a couple, they may naturally have more physical contact.
古い表現だが『肌を許す』は親密になるという意味だ。
It's an old expression, but '肌を許す' means to become intimate.
Surface; grain; texture — referring to the surface quality or grain (e.g., of wood), or tactile feel.
この机は木肌がきれいで、触り心地がいい。
This desk has a beautiful wood grain and feels nice to the touch.
新しい生地は肌触りが柔らかい。
The new fabric has a soft texture to the touch.
紙の肌目によってインクののりが変わることがある。
The paper's surface grain can affect how the ink takes.
Disposition; temperament; type — used to describe compatibility or the fit between people's personalities (e.g., '肌が合う').
新しい同僚とは肌が合い、一緒に働きやすい。
I get along well with the new colleague; they're easy to work with.
彼とは価値観が違って肌が合わないと感じる。
I feel we don't click; our values differ and we aren't compatible.