To fall into ruin or decline; to be reduced to poverty or low status (used for people or families who have lost fortune or position).
かつて裕福だった家族が不運で落ちぶれてしまった。
A family that was once wealthy fell into ruin due to misfortune.
彼は酒に溺れて仕事を失い、すっかり落ちぶれた。
He drowned himself in alcohol, lost his job, and utterly fell from grace.