Everyone; anyone — similar to 'dare demo' but more emphatic, often used in affirmative statements (e.g., 'anyone will ...').
誰しも失敗することはあるから、あまり責めないでほしい。
Everyone makes mistakes sometimes, so please don't be too hard on them.
初めてのことには誰しも不安を感じるものだ。
Anyone feels uneasy when doing something for the first time.
成功者の多くは、誰しもが簡単にできる道を避けたわけではない。
Many successful people didn't simply avoid the easy path that anyone could take.
With a negative verb it can function like 'no one' (e.g., 'dare shimo ... nai' meaning 'nobody ...'), depending on context.
この件の真相を知っている者は誰しもいない。
There is no one who knows the truth about this matter.
証拠がなければ、誰しも有罪だとは言えない。
Without evidence, no one can be said to be guilty.