To be left without means of sustenance; to become homeless or destitute — to be cast out into the streets and at a loss for what to do.
工場の倒産で多くの労働者が路頭に迷った。
When the factory went bankrupt, many workers were left destitute.
貯金が底をつき、彼は路頭に迷う寸前だった。
His savings ran out and he was on the verge of being homeless.
失業保険が切れると、家族は路頭に迷う恐れがある。
If unemployment benefits run out, the family risks being left destitute.