Contempt or disdain; to look down on someone or treat them with scorn. Can be used as a noun or as the suru-verb '軽蔑する'.
彼女は相手を軽蔑するような目で見た。
She looked at the other person with a contemptuous gaze.
その発言は多くの人の軽蔑を買った。
That remark earned the contempt of many people.
人を軽蔑する態度は関係を壊す原因になる。
An attitude of looking down on others can ruin relationships.