A suffix attached to verb masu-stems meaning 'do something continuously/throughout/all the way' (e.g. ～し通し, ～通しで).
彼は朝から晩まで働き通しで、休日も休めない状態だ。
He worked nonstop from morning till night and can't even rest on his days off.
コンサートは休憩なしの通し公演だった。
The concert was a through performance with no intermission.
説明を聞き通しで、質問する暇もなかった。
I listened to explanations the whole time and didn't even have a chance to ask questions.
子どもたちは一日遊び通しで、夜にはぐっすり眠った。
The children played all day and slept soundly at night.