Familiarity or intimacy; also used for a regular place or an acquaintance you know well.
この店は昔からの馴染みだから、店主とも顔なじみだ。
I've been going to this shop for a long time, so I'm familiar with the owner.
彼には仕事上の馴染みが多く、相談しやすい。
He has many acquaintances at work, so he's easy to consult with.
長く住むとその町に馴染みが出てくる。
If you live somewhere for a long time, you become familiar with the town.