Difficult or unpleasant to live in; not comfortable or convenient for daily life.
車がないと生活が不便で、ここは住みにくいと思う。
I think this place is hard to live in without a car because daily life is inconvenient.
古いアパートは寒くて住みにくい。
The old apartment is cold and unpleasant to live in.
治安が悪くて、子どもを育てるには住みにくい地域だ。
The area is bad for raising children; it's difficult to live in because of poor safety.