Indicates that there is no problem or obstacle; everything is all right or acceptable.
明日の予定は問題ないです。予定どおり行きましょう。
There are no problems with tomorrow's schedule. Let's go as planned.
そのやり方で問題ないと思いますよ。
I think that method is fine/no problem.
試験の結果、特に問題ないと先生から言われた。
About the exam results, the teacher said there was nothing wrong.