To raise one's voice; to shout, scream, or cheer (physically producing a loud sound).
試合で観客が大きな声を上げて選手を応援した。
The spectators raised their voices loudly to cheer the players during the match.
驚いて思わず声を上げてしまった。
I was startled and unintentionally cried out.
彼女は叫び声を上げて助けを求めた。
She screamed for help.
To speak up (e.g., protest); to voice one's opinion publicly or demand change (figurative/social use).
労働者たちは待遇改善を求めて声を上げた。
Workers raised their voices demanding better working conditions.
市民が環境問題について声を上げるようになった。
Citizens have started speaking up about environmental issues.
不正を見つけたら、ためらわずに声を上げるべきだ。
If you find wrongdoing, you should not hesitate to speak up.