To insert or thrust something into something else (transitive) — e.g., plugging in a plug, inserting a letter into an envelope.
彼は充電器のプラグをコンセントに差し込んだ。
He plugged the charger into the outlet.
カードをスロットに差し込むと、画面に認識される。
When you insert the card into the slot, it is recognized on the screen.
To come in (of light); to shine or stream in (intransitive). Also written 射し込む.
朝日がカーテンの隙間から差し込んできた。
Morning sunlight streamed in through the gap in the curtains.
地下室にもわずかに外の光が差し込んでいた。
A little outside light was seeping into the basement.
To feel a sharp, stabbing pain (in the chest, stomach, etc.); often used in the phrase 'a pain that stabs/strikes'.
食後に胃が差し込むような痛みを感じたので、医者に行った。
After eating I felt a stabbing pain in my stomach, so I went to the doctor.
突然、腰に差し込むような痛みが走った。
Suddenly a stabbing pain ran through my lower back.